Bahadoran · 2011 · European journal of clinical nutrition
Oxidative stress markers in patients with diabetes
Would four weeks of broccoli sprout powder intake change oxidative stress markers in patients with type 2 diabetes?
Human · randomized double-blind controlled trial
Key findings
Markers of oxidative damage
Treatment effects were reported as reductions in MDA, oxidized LDL, and the oxidative stress index (OSI).
Changes in antioxidant capacity
Total antioxidant capacity (TAC) increased, while total oxidant status (TOS) showed no effect.
Short-term biomarker study
Blood markers were measured over four weeks.
Study design
Eighty-one patients were assigned to 10g/day powder, 5g/day powder, or placebo. Sixty-three were included in the final analysis; blood markers of antioxidant capacity and oxidative damage were compared at baseline and after four weeks.
- Participants
- 81 assigned / 63 analyzed
- Intake and observation
- Sprout powder 5 or 10g/day
4 weeks · placebo controlled - Measures
- TAC · MDA · oxidized LDL · OSI
Study context
These are the four-week blood marker results. The sample size and intake conditions match Bahadoran's 2012 report on insulin resistance and lipids.
Original paper and sources
Broccoli sprouts reduce oxidative stress in type 2 diabetes: a randomized double-blind clinical trial.
- Journal
- European journal of clinical nutrition · 2011 · 65(8): 972-977
- First published
- 2011-05-11