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Broccoli Sprout and Sulforaphane Research

Gastric health

Stomach Health

Helicobacter bacteria and gastric inflammation: changes observed after sprout intake

In an eight week trial of adults with Helicobacter infection, bacterial colonization and gastric inflammation markers fell. A separate trial compared sprout powder and standard eradication therapy alone and combined.

2 studies
Human research
48 participants
Eight week sprout intake trial
8 weeks
Duration of sprout intake
Image of gastric health research using a paper stomach model and broccoli sprouts

Gastric health · research results at a glance

2 studies

Broccoli sprouts and gastric inflammation markers

Broccoli sprouts and gastric inflammation markers
Study and participantsIntake and observationFindings and context
Yanaka · 2009

Adults with H. pylori infection
48 participants · sprout comparison trial

Broccoli sprouts 70 g/day
Eight weeks · alfalfa control

Reduced bacterial colonization and gastric inflammation markers after eight weeks of intake

Finding: In a trial of 48 adults with infection, bacterial colonization and gastric inflammation markers were lower in the broccoli sprout group.

Context: Participants took 70 g/day for eight weeks. Two months after stopping intake, the markers returned to baseline.

Sprout powder and standard eradication therapy

Sprout powder and standard eradication therapy
Study and participantsIntake and observationFindings and context
Mirmiran · 2014

People with type 2 diabetes and Helicobacter infection; 86 randomized, 77 completed

Sprout powder 6 g/day for 28 days; standard eradication therapy for 14 days; comparison of separate and combined treatments

Eradication results for three interventions

Finding: Eradication rates among completers were 89.3% with standard therapy, 56.0% with sprout powder, and 91.7% with both.

Context: Completers numbered 28, 25, and 24 in the standard therapy, powder, and combination groups, respectively. A stool antigen test was used after four weeks.

Sources

  1. Yanaka et al. Cancer Prev Res. 2009;2:353-360.DOI 10.1158/1940-6207.CAPR-08-0192
  2. Mirmiran, et al. J Diabetes Metab Disord. 2014;13:64.DOI 10.1186/2251-6581-13-64