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Mirmiran · 2014 · Journal of diabetes and metabolic disorders

Blood pressure and lipids with eradication therapy plus sprout powder

How do risk markers change when eradication therapy is combined with sprout powder in patients with diabetes and H. pylori infection?

Human · randomized trial of three interventions

Concept image introducing cardiovascular and lipid research

Key findings

Blood pressure changes under the combined condition

Reductions in systolic and diastolic blood pressure were reported in the group receiving standard eradication therapy plus sprout powder.

Difference in eradication rates by intervention

Among completers, eradication rates were 89.3% with standard therapy, 56.0% with powder alone, and 91.7% with both.

Pre–post change in inflammation markers

A decrease in hs-CRP was reported in the powder-only group. A subgroup analysis after eradication was also conducted.

Study design

Eighty-six participants were assigned to standard eradication therapy, 6 g/day of sprout powder for 28 days, or both. Seventy-seven completed the study; blood pressure, lipids, and high-sensitivity CRP were assessed alongside eradication outcomes.

Participants
Diabetes with H. pylori infection
Intake and observation
Powder 6 g/day for 28 days
Eradication therapy, powder alone, or both
Measures
Eradication outcome · blood pressure · hs-CRP

Study context

This study involved patients with diabetes and H. pylori infection. Blood pressure reductions were reported in the group receiving both eradication therapy and sprout powder.

Original paper and sources

A comparative study of broccoli sprouts powder and standard triple therapy on cardiovascular risk factors following H.pylori eradication: a randomized clinical trial in patients with type 2 diabetes.

Mirmiran P, Bahadoran Z, Golzarand M, Zojaji H, Azizi F.

Journal
Journal of diabetes and metabolic disorders · 2014 · 13: 64
First published
2014-05-28