Lynch · 2017 · Global advances in health and medicine
Long-term family follow-up after the initial trial
What changes did families report after the trial?
Human · follow-up case report from an earlier trial
Key findings
Responses from 16 families
Families of 16 of the 26 participants provided follow-up information.
Experience with continued use
At follow-up, nine participants were still using supplements, and one planned to use them.
Positive experiences at the case-report level
Some families described behavioral and communication changes.
Detailed results
The study asked families how daily life changed after the trial.
A follow-up case report on some participants who took sulforaphane in the 2014 Singh trial. The researchers confirmed 2014 information through ongoing contact with families and updated some accounts through summer 2016.
Families described changes in daily life, including communication, emotional stability, going out, and shared activities. These are accounts of each family's use and observations.
| Reported circumstances | Participants |
|---|---|
| Still using it | 9 participants |
| Seeking another supplement | 1 participant |
| Reconsidering continued use after a recent health problem | 2 participants |
| Change was reported to persist after discontinuation. | 1 participant |
| No clear behavioral change experienced | 3 participants |
Usage status based on the paper's follow-up case classifications.
Higher response rate among families of initial responders
Of 26 original sulforaphane recipients, 16 families responded. Fourteen of 17 initial improvers and two participants without improvement responded to follow-up contact. Initial responders made up a larger share of respondents.
Observations in daily life
Family observations covered communication and behavior as well as participation in daily life and caregiving experiences. The composition, formulation, and duration of commercially available material used after the trial differed between families.
Study design
After the initial controlled trial, the research team asked families about their use experiences. Their responses were compiled in a follow-up case report.
- Participants
- Of 26 SFN recipients in the Singh trial,
16 families responded to follow-up contact - Intake and observation
- Experience using commercial supplements after the trial
Follow-up through summer 2016 - Measures
- Family and caregiver narratives, continued or discontinued supplement use
Study context
A follow-up case report on some participants from Singh 2014. Families of initial responders made up a larger share of respondents.
Original paper and sources
Sulforaphane from Broccoli Reduces Symptoms of Autism: A Follow-up Case Series from a Randomized Double-blind Study.
- Journal
- Global advances in health and medicine · 2017 · 6: 2164957X17735826
- First published
- 2017-10-26