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López-Chillón · 2019 · Clinical nutrition (Edinburgh, Scotland)

Seventy days of sprout intake and inflammatory markers

How did inflammatory markers change when adults with overweight added fresh sprouts to their usual diet?

Human · uncontrolled before-and-after intake trial

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Key findings

Change in IL-6 from baseline

Mean IL-6 decreased from 4.76pg/mL at baseline to 2.11pg/mL after 70 days.

Intervention using everyday food

This study added fresh sprouts to meals rather than using purified compounds and examined an amount feasible in a daily diet.

Inflammatory markers measured

Blood inflammatory markers, including IL-6, were measured.

Inflammatory Marker · IL-6

Within-person mean before and after · pg/mL

Inflammatory Marker · IL-6 chart. Exact values and units appear in the data table below.

40 adults with excess weight · no parallel control group

Fresh broccoli sprouts 30 g/day

Read the original paper and sources ↓
View values and units
Within-person mean before and after · pg/mL
GroupValue
Baseline4.76
Day 702.11

Study design

Forty adults with overweight consumed 30g/day of fresh broccoli sprouts for 70 days. A 70-day follow-up period on their usual diet without sprouts followed; there was no parallel control group.

Participants
40 adults with overweight
intake trial without a parallel control group
Intake and observation
Fresh sprouts 30g/day · 70 days
follow-up afterward
Measures
IL-6 · blood marker of inflammation

Study context

This uncontrolled study compared overweight adults before and after 70 days of intake, then followed them for another 70 days after they resumed their usual diet.

Original paper and sources

Effects of long-term consumption of broccoli sprouts on inflammatory markers in overweight subjects.

López-Chillón MT, Carazo-Díaz C, Prieto-Merino D, Zafrilla P, Moreno DA, Villaño D.

Journal
Clinical nutrition (Edinburgh, Scotland) · 2019 · 38(2): 745-752
First published
2018-03-13