Armah · 2015 · Molecular nutrition & food research
GLR-rich broccoli and LDL
Would LDL change differently with standard broccoli versus a glucoraphanin-rich variety?
Human · two randomized dietary trials
Key findings
First trial
LDL decreased 1.8% from baseline with standard broccoli and 7.1% with the GLR-rich variety.
Second trial
They decreased by 2.5% and 5.1%, respectively. The pooled between-group comparison of the two trials in the original paper had p=0.031.
Unit of comparison
The graph shows each group's percentage decrease from baseline. Between-group differences were assessed in a pooled analysis of two trials.
LDL Reduction · Trial 1
Reduction from baseline · %
37 participants · longer bars indicate a larger reduction
Broccoli 400 g/week · 12 weeks
Read the original paper and sources ↓View values and units
| Group | Value |
|---|---|
| Standard broccoli | 1.8 |
| High-GLR broccoli | 7.1 |
LDL Reduction · Trial 2
Reduction from baseline · %
93 participants · pooled between-group p = 0.031 in the original paper
Broccoli 400 g/week · 12 weeks
Read the original paper and sources ↓View values and units
| Group | Value |
|---|---|
| Standard broccoli | 2.5 |
| High-GLR broccoli | 5.1 |
Study design
Two independent trials enrolled 37 and 93 participants, 130 in total. Participants consumed 400g of broccoli per week for 12 weeks, comparing a standard variety with a GLR-rich variety.
- Participants
- Two independent randomized trials
37 + 93 = 130 participants - Intake and observation
- Broccoli 400g/week · 12 weeks
GLR-rich versus standard variety - Measures
- Plasma LDL cholesterol
Study context
Two independent trials compared standard broccoli with a GLR-rich variety. Blood LDL after 12 weeks was measured.
Original paper and sources
Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: Evidence from randomised controlled trials.
- Journal
- Molecular nutrition & food research · 2015 · 59(5): 918-926
- First published
- 2015-04-07