Talalay · 2007 · Proceedings of the National Academy of Sciences of the United States of America
Topical sprout extract and UV erythema
Does applying sprout extract to skin change the redness response after UV exposure?
Human and animal · topical skin experiments
Key findings
Mean reduction in erythema response
In humans, post-UV erythema was 37.7% lower on average (p=0.025). Individual reductions ranged widely from 8.37% to 78.1%.
Response of cellular defense pathways
Responses of phase 2 protective enzymes in skin were examined to propose a cellular defense mechanism against UV damage.
Topical application trial
Results from applying extract directly to skin.
Study design
A sulforaphane-rich extract was applied to the skin of six healthy adults before exposure to several UV intensities. Animal experiments on skin inflammation and protective enzymes were also conducted.
- Participants
- Six healthy participants
Topical skin study - Intake and observation
- Sprout extract applied to skin
Erythema measured after UV exposure - Measures
- Skin erythema after UV irradiation
Study context
Extracts were applied directly to the skin of six healthy participants. Erythema after UV exposure was measured.
Original paper and sources
Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation.
- Journal
- Proceedings of the National Academy of Sciences of the United States of America · 2007 · 104(44): 17500-17505
- First published
- 2007-10-23