Kikuchi · 2021 · Journal of Functional Foods
Four weeks of intake, sleep satisfaction, and melatonin
Would glucoraphanin intake change outcomes in healthy adults who feel their sleep quality is poor?
Human · randomized double-blind pilot trial
Key findings
Four-week sleep assessment
In a pilot trial of 18 adults, sleep satisfaction and melatonin markers in the intake group increased from baseline. The difference from the placebo group was not statistically significant.
Sleep Satisfaction · Before and After 4 Weeks
Mean VAS score in the intake group · points
Within-group values; no significant between-group difference established
18 participants total · GLR 30 mg/day
Read the original paper and sources ↓View values and units
| Group | Value | Standard deviation |
|---|---|---|
| Baseline | 4.8 | 1.60 |
| Week 4 | 6.4 | 1.90 |
Detailed results
Before-and-after measures in the intake group
The sleep satisfaction VAS changed from 4.8±1.6 to 6.4±1.9, and the time-integrated melatonin concentration changed from 109.7±80.0 to 143.5±79.9pg/mL·h.
Study design
Eighteen healthy adults were divided into sprout extract and placebo groups. They consumed 30mg/day of glucoraphanin for four weeks, and sleep satisfaction, melatonin, and prostaglandin markers were compared.
- Participants
- Japan · 18 healthy adults with sleep complaints
compared with ingredient-free capsules - Intake and observation
- Glucoraphanin 30mg/day
4 weeks · two-group comparison
sleep questionnaire and melatonin measured - Measures
- Sleep satisfaction VAS · melatonin AUC
Study context
This exploratory trial measured sleep satisfaction and melatonin and prostaglandin concentrations at multiple times.
Original paper and sources
Effects of glucoraphanin-rich broccoli sprout extracts on sleep quality in healthy adults: An exploratory study
- Journal
- Journal of Functional Foods · 2021 · 84: 104574
- First published
- 2021-09