Redefining health at the cellular level.
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Ali · 2023 · Frontiers in oncology

Review of cancer-related molecular pathways of sulforaphane

Which cancer cell pathways and epigenetic regulatory mechanisms have been studied in relation to sulforaphane?

Literature review · molecular mechanisms

Concept image introducing cancer mechanism research

Key findings

How multiple pathways connect

The authors discuss diverse molecular pathways, including cell cycle, apoptosis, oxidative stress, and epigenetic regulation.

Cell, animal, and clinical literature

The authors reviewed both cellular and animal mechanisms and human clinical outcomes.

Questions for future research

The authors discuss the need for standardized doses and further research.

Study design

Molecular mechanisms related to cancer were reviewed using literature from PubMed, Scopus, Web of Science, and other databases.

Participants
Review of mechanisms in existing studies
Synthesis of existing literature
Intake and observation
Review of cancer-related molecular pathways
gene regulation, apoptosis, and more
Measures
Cell cycle · apoptosis · epigenetics

Study context

This review summarized cancer-related molecular pathways described in existing cell, animal, and clinical literature.

Original paper and sources

Anticancer properties of sulforaphane: current insights at the molecular level.

Asif Ali M, Khan N, Kaleem N, Ahmad W, Alharethi SH, Alharbi B, Alhassan HH, Al-Enazi MM, Razis AFA, Modu B, Calina D, Sharifi-Rad J.

Journal
Frontiers in oncology · 2023 · 13: 1168321
First published
2023-06-16